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Increase human papillomavirus (HPV) vaccination uptake

Woman vaccinating child


HPV vaccination provides safe, effective, and long-lasting protection against cancers caused by HPV. HPV infections can cause warts, cervical cancer, and cancers of the anus, penis, vulva, vagina, and oropharynx. Estimates show HPV vaccination could prevent 31,200 cancers every year. The 2017 National Immunization Survey shows only 66% of adolescents aged 13–17 years have started and only 49% have completed the HPV vaccine series1. Also, fewer teens in rural areas are getting HPV vaccines compared with teens in urban areas. These data highlight the need for focused efforts to follow up with adolescents who are due for the vaccines.

How is the National Partnership addressing HPV vaccination?

As one of its priorities, the Comprehensive Cancer Control National Partnership (CCCNP) is focused on improving the HPV vaccination rates among 11- to 12-year-old boys and girls across the U.S. The HPV work group started out by identifying and mapping the multiple partner activities related to HPV vaccination, which allowed the work group to identify opportunities for collaboration.

In 2016, the work group supported 11 state teams with high cervical cancer mortality and low vaccination rates by bringing them together for an in-person workshop to learn about proven, evidence-based strategies and participate in dedicated time to develop collaborative, one-year action plans to increase vaccine uptake. Post-workshop technical assistance was provided to help state teams with implementation of the action plan and to continue sharing evidence-based strategies and resources. 

In 2018, an additional 22 states participated in HPV workshops, and these state teams will receive post-workshop technical assistance up to June 2019. As a part of 2018–2019 action plan, the CCCNP HPV work group is focusing on efforts to better communicate the work of the national partners and to improve HPV vaccination uptake, with a focus on rural health and health disparities.


HPV Roundtable

The National HPV Vaccination Roundtable (HPV Roundtable) is a trusted coalition of public, private and voluntary organizations and experts dedicated to reducing incidence of and mortality from HPV cancers in the United States and provides several resources for various stakeholders (parents, clinicians, state and local coalitions) involved in similar efforts.

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The Centers for Disease Control and Prevention (CDC) provides HPV resources for parents and the public, health care professionals, partners and programs.

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The National Cancer Institute (NCI) hosts the Research Tested Intervention Programs (RTIPs) website, which is a searchable database of evidence-based cancer control intervention and program materials for program planners and public health practitioners.

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Cancer Control P.L.A.N.E.T.

The Cancer Control P.L.A.N.E.T. portal provides access to data and resources that can help planners, program staff and researchers design, implement and evaluate evidence-based cancer control programs. 

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1. Walker TY, Elam-Evans LD, Yankey D, et al. (2018). National, Regional, State, and Selected Local Area Vaccination Coverage Among Adolescents Aged 13–17 Years — United States, 2017. MMWR Morb Mortal Wkly Rep, 67:909–917.